Cloning Dolly, How and Why?
Presented on June 22, 2001 by Keith Campbell, Ph.D., University of Nottingham
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"I want to try to explain to people...the positive uses for this technology, the benefits that it may have for human therapeutic medicine and improving the quality of life for people with certain genetic disorders." - Keith Campbell, interview 6/22/01
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Keith Campbell, along with colleague Ian Wilmut of Roslin Institute, took biological science to a new level with the 1996 creation of Dolly the sheep. While prior success had been achieved with the births of sheep derived from cultured embryo cells, significant milestones in themselves, Dolly was special because she was the first animal to be cloned from a somatic, or body cell. A major key to their success was Campbell's understanding of the cell cycle-the steps involved in cell division-and its technical implications.
Since Dolly's arrival, great interest and debate has emerged concerning the potential for human cloning. Campbell opposes pursuit of this application. Instead, he emphasizes the almost limitless potential for medical advances that cloning and related technology might bring-new ways to prevent and treat genetic abnormalities, disease and disability, more knowledge of the secrets of cell differentiation, and a better understanding of fetal development.
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Lecture Video
Pre-Lecture Video
Lecture transcript
- Part 1 - The Biology of Cloning
- Part 3 - Cell Cycle Phase G0-Quiescence
- Part 4 - Practical Applications
About Keith Campbell
Medical Terminology
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